Researchers at King’s College London found that the drug Tideglusib stimulates the stem cells contained in the pulp of teeth so that they generate new dentine – the mineralised material under the enamel.
Teeth already have the capability of regenerating dentine if the pulp inside the tooth becomes exposed through a trauma or infection, but can only naturally make a very thin layer, and not enough to fill the deep cavities caused by tooth decay.
But Tideglusib switches off an enzyme called GSK-3 which prevents dentine from carrying on forming.
Scientists showed it is possible to soak a small biodegradable sponge with the drug and insert it into a cavity, where it triggers the growth of dentine and repairs the damage within six weeks.
The tiny sponges are made out of collagen so they melt away over time, leaving only the repaired tooth.
That is by far the coolest thing I’ve heard this year.
nittany-tiger: Was it when Chef posted a pic of himself? I barely remember any sort of dramatic reveal, unless I'm just so used to chicks online actually being guys it's just no big deal anymore.
Was a texpost. Very heartfelt. Everyone was supportive. And forgiving. Very.
